Medical Researches
Likely Ineffective
Based on 16 Researches
We explored the effects of magnesium treatment in a unique case involving a 62-year-old woman with stage IV colon cancer undergoing oxaliplatin therapy. Shortly after her first infusion, we observed that she experienced significant neurological symptoms, including right hemibody paresthesia, muscle cramping in her right calf, and dysphonia.
To address these symptoms, she was administered intravenous magnesium sulfate along with calcium gluconate. Remarkably, within three hours, all her symptoms resolved. While this case suggests that magnesium can provide relief from cramps and other neurological side effects, it is important to note that magnesium was used in conjunction with other medications, making it challenging to assess its isolated effectiveness.
For future doses, the oxaliplatin was adjusted by reducing the dose and extending the infusion duration, which minimized her symptoms to occasional mild paresthesia. In summary, while magnesium showed promise in this case, further research is needed to determine its specific impact on leg cramps in a clearer, more controlled manner.
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Magnesium oxide treats leg crampsA randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps.
High relevance for magnesium use
We conducted a study to evaluate how effective magnesium oxide monohydrate (MOMH) is in treating nocturnal leg cramps (NLC). This was a randomized, double-blind, placebo-controlled trial involving multiple centers in Ukraine, where participants took either MOMH or a placebo nightly for 60 days.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
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We sought to understand the effectiveness of oral magnesium in treating leg cramps experienced by pregnant women. Our study was well-structured, involving a double-blind, randomized, placebo-controlled design. It included 86 healthy pregnant women between 14 to 34 weeks of gestation who encountered leg cramps at least twice a week, and we followed them over a four-week period.
At the end of the study, we discovered that the women taking magnesium bisglycinate chelate (300 mg per day) reported a significant reduction in cramp frequency—86% experienced at least a 50% drop compared to only 60.5% of those taking the placebo. Additionally, those on magnesium also noted a notable decrease in cramp intensity, with 69.8% achieving a similar improvement versus just 48.8% in the placebo group.
Encouragingly, we found no major side effects reported in either group, such as nausea or diarrhea. Our findings suggest that magnesium supplements can effectively reduce both the frequency and severity of leg cramps during pregnancy, offering a potential treatment option for women dealing with this common issue.
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Magnesium's potential against crampsRandomised, cross-over, placebo controlled trial of magnesium citrate in the treatment of chronic persistent leg cramps.
Directly investigates magnesium's impact
We set out to investigate whether magnesium citrate could be an effective remedy for those who experience bothersome leg cramps, particularly at night. In our study, we used a randomised, double-blind, cross-over, placebo-controlled design to ensure reliable results. Participants suffering from regular leg cramps were recruited and given either magnesium citrate or a matching placebo over six weeks.
Our findings revealed that those who began the trial with the placebo experienced an average reduction in cramps when taking magnesium, with a median of 5 cramps compared to 9 on the placebo. Moreover, a notable percentage of participants felt that the magnesium treatment had indeed helped them, with 78% reporting benefits, as opposed to 54% who felt the placebo was effective.
While these results suggest that magnesium may have a positive impact, it’s essential to mention that the impact on cramp severity and duration wasn’t significantly different between the two groups. Additionally, some participants did report experiencing diarrhoea as a side effect of magnesium. Overall, we believe magnesium shows promise in alleviating nocturnal leg cramps and recommend further research to fully evaluate its effectiveness.
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We explored the effectiveness of magnesium treatment for leg cramps during pregnancy through a review of five randomized trials involving 352 women.
The trials varied in quality, but interestingly, they included comparisons of different treatments such as calcium and sodium chloride against placebos. While the placebo-controlled trial that investigated calcium did not show any significant benefits, there were hints of promise for magnesium.
For those looking for relief from troublesome leg cramps, our analysis indicated that magnesium—specifically in the forms of magnesium lactate or citrate—might help. Taking 5mmol in the morning and 10mmol in the evening seemed to provide the best results.
However, the evidence remains mixed, and we couldn't pinpoint any strong benefits from other combinations or supplements tested. So, while magnesium might be beneficial, it’s essential to approach it as one option among many.
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User Reviews
Excellent
Based on 15 Reviews
UPDATE: These supplements continue to work for me. I am usually sceptical about new products, especially when they receive rave reviews. I suffered from leg and foot cramps at night, causing me to bolt out of bed in pain. Potassium and magnesium were said to be helpful, and after taking two a day for a week or two, all my cramping ceased. I'm a firm believer in the power of the right supplements.
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Finally, I've had a good night's sleep. After reading reviews, I decided to try this for my leg cramps, which were not limited to charley horses but also affected my feet. I previously woke 2-4 times nightly needing to soak my legs. This product has worked wonders. I started with one pill each morning and evening, eventually reducing to one before bed. The improvement in my sleep has been incredible.
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My mother was experiencing severe leg cramps that resulted in bruising. I purchased these tablets for her at 88 years old. After consulting her doctor, he confirmed they were suitable for her condition. She has been taking them for two months, and her leg cramps have completely ceased. I would rate this product a solid 10!
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This is my second purchase of this brand on Amazon after reading positive reviews. I had been suffering from leg cramps, but after three months of use, I have not experienced another episode. I did have one muscle spasm in my back, but I believe that was due to an awkward sleep position.
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I needed a solution for night-time leg cramps and regularity. These tablets really work for me! I take three every evening, and I no longer experience leg cramps. They also aid in keeping my digestive system functioning well. However, three might be excessive for some; one or two could suffice based on individual needs.
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